▶ PINEALON · SUBTOPIC · DOSING LITERATURE

PINEALON Dosing Literature

For Laboratory Research Use Only. The content below describes dose ranges as reported in peer-reviewed publications. This page does not recommend any dose for human use. No clinical claim is made. Always consult the original source publication.

SCOPE OF THIS PAGE

This page documents the published-literature dose ranges that appear in trials and animal studies of PINEALON. Every dose mention is bound to a citation (author, year, PMID where available). The PEPPUDEX wiki phrases these as descriptive observations of the research record, not as instructions to the reader.

ROUTES OF ADMINISTRATION IN PUBLISHED RESEARCH

The published research record for PINEALON reports the following route(s) of administration: Intranasal (Russian clinical literature), Subcutaneous (research), Oral (research). Route selection in a study reflects pharmacokinetic considerations specific to that protocol and is not a recommendation for any human use of PINEALON.

PHARMACOKINETIC HALF-LIFE

Published pharmacokinetic data report a half-life for PINEALON of approximately Short (minutes) plasma · longer CNS retention reported. Half-life is the kinetic parameter that frames the dosing rhythm chosen in trial design. It is a measurement, not a recommendation.

CITED DOSE RANGES IN THE LITERATURE

The peer-reviewed sources below report dose ranges, frequencies, and durations used in studies of PINEALON. Refer to the original publication for full protocol detail.

Khavinson VK, Kuznik BI, Tarnovskaya SI (2012) reports the PINEALON protocol used in Short peptides and gene regulation in aging, published in Bull Exp Biol Med. See the source for the protocol-level dose range, frequency, and duration. link
Khavinson VK et al. (2014) reports the PINEALON protocol used in Neuroprotective effects of Khavinson's short peptides in stress models, published in Bull Exp Biol Med. See the source for the protocol-level dose range, frequency, and duration. link

DOSING Q+A FROM LITERATURE

The questions below summarise dosing-relevant entries from the literature record. Each answer is descriptive of published material and is not a recommendation.

▶ What's the half-life of Pinealon?

Short plasma half-life (minutes). CNS retention is reportedly longer. Russian clinical protocols use intranasal administration to enhance brain delivery.

▶ What's the research dose?

Russian preclinical and clinical literature describes 50-200 mcg per administration. No standardized human dose. This wiki does not recommend any human dose.

STORAGE OF THE REFERENCE COMPOUND

Lyophilized · 2-8 °C, 24 months

Reconstituted · 2-8 °C, 28 days

Storage conditions describe the stability of the research-grade reference material, not a dosing protocol.

RECONSTITUTION MATH (CALCULATOR)

The PEPPUDEX reconstitution calculator at /calculator returns volume-per-dose math given vial mg, BAC mL, and a target dose in mcg. The calculator performs arithmetic only. It does not recommend a dose. Any number entered by a researcher must come from their own protocol design or the cited literature.

REGULATORY CONTEXT

FDA · Not FDA-approved. Research-use only in the United States.

WADA · Not currently listed on the WADA Prohibited List (2026).

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▶ LAST UPDATED · 2026-05-25