BDNF Axis
BDNF (Brain-Derived Neurotrophic Factor) is a 119-residue homodimeric neurotrophin acting through TrkB receptor tyrosine kinase. It drives synaptic plasticity, long-term potentiation, and neuronal survival in hippocampus, cortex, and basal forebrain. Semax upregulates hippocampal BDNF / TrkB expression in rodent models.
