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MECHANISM

Actin Cytoskeleton

Actin is the most abundant cytoskeletal protein in eukaryotic cells, cycling between monomeric G-actin and polymerized F-actin. G-actin sequestering proteins (Thymosin Beta-4, and its synthetic fragment TB-500) shift the equilibrium to promote cell migration — particularly endothelial cells and stem cells in tissue-repair contexts.

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